Beta2 adrenergic receptor (ADRβ2) haplotype pair (2/4) is associated with severe asthma.

PLoS One · 2014 · PMC3972120 · PMID 24691493

Europe PMC DOI

hedged sentences

0.0008

closest p · 0.0× alpha

0.0700

boldest claim

The sentences

a positive trendp = 0.0008actually significant

The association was strengthened by a positive Trend test for mild, moderate and severe asthma (Mild OR 1.0; Moderate OR 1.42. 95%CI 1.16, 1.74; Severe OR 2.01, 95%CI 1.64, 2.46; p = 0.0008).

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an overall trendp = 0.07so close (0.05 < p ≤ 0.1)

While numbers were too small for further statistical analysis there was an overall trend for a higher frequency of pooled novel haplotypes in severe asthmatics compared with moderate, mild or non-asthmatics (p = 0.07).

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