Harnessing the immune system to provide long-term survival in patients with melanoma and other solid tumors.

Oncoimmunology · 2014 · PMC3973659 · PMID 24719793

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highly significantno p-value reported

The effect of IFN-α2b is highly significant in patients with Stage IIB and sentinel node (SN)-positive Stage III melanoma, but blunted in palpable node-positive patients. 12 Adjuvant IFN-α2b has been shown to consistently reduce the risk of disease recurrence, distant metastases, and death by 35–44% among patients with SN-positive disease and an ulcerated primary tumor.

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