Influence of wiring cost on the large-scale architecture of human cortical connectivity.

These findings render the even spatially highly significant, well-confined and more tightly intra-connected cortical s-core a more appropriate candidate for a putative central cortical core [12] , while the rich-club seems to be more suited for fulfilling the role of a ‘dynamic router’ [25] , a set of distributed cortical hub regions predominantly connecting their local neighbourhoods with distant parts and the s-core of the cortex.

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