Barely Significant
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Candida vaginitis: when opportunism knocks, the host responds.

PLoS Pathog · 2014 · PMC3974868 · PMID 24699903

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highly significantno p-value reported
Accordingly, although much insight has been gained from extensive studies in this field, scientific endeavors aimed at preventive therapies, improved diagnostics, and pathogenesis will require careful attention to the immunopathogenic response to ultimately combat this highly significant, opportunistic fungal disease.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.