highly significantp = 0.001
When we analyzed TCs and controls separately, we did not only find a highly significant reduction in sRAGE but also in esRAGE levels (sRAGE 188.6±40.5 vs. 364.8±28.6; p = 0.001; fig. 7(c) ; esRAGE 334.6±35.7 vs. 412.9±21.3; p = 0.023; fig. 7(d) ).