Barely Significant
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Some amino acids levels: glutamine,glutamate, and homocysteine, in plasma of children with chronic kidney disease.

Int J Biomed Sci · 2014 · PMC3976446 · PMID 24711748

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highly significantno p-value reported
( 39 ) had reported that a highly significant rise of plasma glutamic acid and hydroxyproline was detected in nephrotics and these changes in AA levels occurred before the rise in serum creatinine.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.