In the HER2-negative group ( n = 2,727, 219 events) patients receiving only AHT (HR = 2.33, 95%-CI 1.40–3.87, P = 0.001) or only CHT (HR = 3.15, 95%-CI 1.61–6.16, P = 0.001) or no adjuvant therapy at all (HR = 4.91, 95% CI 2.81–8.59, P < 0.001) showed a highly significant decrease in OS compared to patients with both CHT and AHT (reference group) ( Table 6(b) ). 4.
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Guideline concordant therapy prolongs survival in HER2-positive breast cancer patients: results from a large population-based cohort of a cancer registry.
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