28 Conformation state shifting from the T state to the T′ state or the R state upon R9C mutation would be coupled to functionality loss and make the R9C-PLB conformation studies extremely significant.
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Secondary structure, backbone dynamics, and structural topology of phospholamban and its phosphorylated and Arg9Cys-mutated forms in phospholipid bilayers utilizing 13C and 15N solid-state NMR spectroscopy.
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