Coarse grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges.

J Phys Chem B · 2014 · PMC3983386 · PMID 24547945

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highly significantno p-value reported

While the extent to which this holds true for non-polypyrimidine bulges is unclear, this finding nevertheless indicates topological constraints to be a highly significant driver of bulge conformation.

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