We observed similar, and sometimes increased, enrichment of active marks in the repressed isolated RTSSs compared to the full set of global RTSSs (Figure 1 ; [Additional file 1 : Figure S1]), and p-values calculated for each overlap also confirmed highly significant overlaps (Methods, [Additional file 1 : Table S18]).
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Chromatin states reveal functional associations for globally defined transcription start sites in four human cell lines.
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