Since the association between venous thrombosis and FVL was reported before, several studies investigated the prevalence and importance of this mutation in different regions of the world and showed that it has a wide range of diversity: A high prevalence in European and Middle-Eastern countries, with a decreasing trend when it goes to the east.[ 25 26 ] The highest prevalence rates have been reported in Mediterranean countries of the Middle-East.[ 27 28 ] The occurrence of FVL in a normal population in Turkey, which extended from Mediterranean area to the western border of Iran at the central Middle-East, varies
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Factor V Leiden does not have a role in cryptogenic ischemic stroke among Iranian young adults.
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