Barely Significant
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Gene targeting of mouse Tardbp negatively affects Masp2 expression.

PLoS One · 2014 · PMC3989299 · PMID 24740308

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The sentences

highly significantp<0.0001actually significant
The absence of Tardbp 2lox/2lox offspring was highly significant (p<0.0001, Chi-square test); the ratio of Tardbp +/+ to Tardbp +/2lox mice (22∶49) fit the expected 1∶2 ratio, consistent with a purely recessive inheritance lethality in the homozygote.

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