Mutational signatures: the patterns of somatic mutations hidden in cancer genomes.

Curr Opin Genet Dev · 2014 · PMC3990474 · PMID 24657537

Europe PMC DOI

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highly significantno p-value reported

lung adenocarcinoma and tumours of the head and neck) confirmed a highly significant elevation of this ‘tobacco smoking signature’ in smokers indicating that it was due to tobacco mutagens.

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