In the high IRI subgroup, there was still a slightly higher risk of diarrhoea in UGT1A1*1/*28 patients (OR=1.39, 95% CI: 0.97–1.98; P =0.07), of borderline significance.
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Association of UGT1A1*28 polymorphisms with irinotecan-induced toxicities in colorectal cancer: a meta-analysis in Caucasians.
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