Koracevic and Atanaskovic [ 19 ] reported that irrespective of whether patients had unilateral or bilateral DELC or if the crease was deep or superficial (< 1 mm), there was no significant correlation between DELC and clinical CAD (not even a trend toward significance).
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Diagonal earlobe crease and coronary artery disease in a Chinese population.
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On par with studies previously documented [ 7 , 14 , 20 , 23 , 31 ] we also found an increasing trend of DELC prevalence with increasing age, but age was not a positive predictor for CAD and the relationship of DELC with CAD was independent of age and sex.
When patients with CAD as determined by coronary artery angiography (CAG) were taken into consideration, a Turkish study of 415 cases shown a highly significant statistically greater prevalence of DELC (51.4%) in those patients with a positive angiogram (as defined as >70% stenosis of the luminal diameter) than in those whose angiogram was normal (15.1%) [ 6 ].