Characterization of genomic vitamin D receptor binding sites through chromatin looping and opening.

PLoS One · 2014 · PMC3999108 · PMID 24763502

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highly significantno p-value reported

Our combined ChIP-seq and FAIRE-seq time course data showed that each of these four domains contained a master VDR binding site, where an increase of VDR binding pairs with 1,25(OH) 2 D 3 -promoted chromatin opening and the presence of a highly significant DR3-type sequence below the peak summit.

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