did not achieve significanceP >0.05
40 Meanwhile, in a Japanese study including 557 primary breast cancer patients, although the T/T genotype tended to be associated with better disease-free survival compared to other genotypes of rs 2279744, this association did not achieve significance ( P >0.05), and no statistically significant correlation was found between prognosis and MDM2 rs 2279744 genotype. 41 The MDM2 promoter rs 2279744 polymorphism influences long-term survival among patients receiving paclitaxel for large primary breast cancers. 42 The relationship between the rs 2279744 polymorphism and cancer was inconsistent.