SDS, a structural disruption score for assessment of missense variant deleteriousness.

Front Genet · 2014 · PMC4001065 · PMID 24795746

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highly significantno p-value reported

The single parameters that best differentiate the groups are the MutationAssesssor prediction for gene set 1 and the PolyPhen2_HVAR prediction for gene set 2, but more notable is the highly significant differentiation for all of the sequence-based scores.

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