These results are highly significant given that the population of older adults in the United States is expected to double by 2050 (Unal et al. 2010 ) and that obesity has increased steadily in this age group from 1999 to 2010 (Fakhouri et al. 2012 ).
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Dichotomous mechanisms of aortic stiffening in high-fat diet fed young and old B6D2F1 mice.
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