Patch clamp studies of human sperm under physiological ionic conditions reveal three functionally and pharmacologically distinct cation channels.

Mol Hum Reprod · 2014 · PMC4004083 · PMID 24442342

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highly significantno p-value reported

As far as we are aware, this is the first evidence that quinidine and 4-AP can activate any type of ion channel and these unusual responses could be highly significant since both substances can induce a ‘hyperactive’ pattern of motility ( Barfield et al. , 2005a ; Alasmari et al. , 2013b ).

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