Mechanistic aspects of hydration of guanine radical cations in DNA.

J Am Chem Soc · 2014 · PMC4004273 · PMID 24689701

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Thus, the formation of Fapy, relative to 8-oxoG may be significant in cellular DNA. 3 , 15 However, the yield of FapyG is much lower than that of 8-oxoG in isolated DNA upon one-electron oxidation in aerated aqueous solutions, 17 and therefore, this particular guanine decomposition product is not considered in the present study.

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