The contribution of viral genotype to plasma viral set-point in HIV infection.

Using the comparison of the resulting log-likelihood values from running the model with and without the tree to estimate significance, both replicates produced highly significant (p<0.0001) heritability estimates of 5.8% (CI 2.9–8.7%) and 5.6% (CI 2.6–8.5%; Table 2 ).

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Only four of the resulting heritability estimates failed to reach significance after Bonferroni correction (though their p-values were still <0.002), resulting in a mean heritability estimate of 5.5% (CI 2.6–8.5%) (data not shown).

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