Barely Significant
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The N-terminal region of the atypical chemokine receptor ACKR2 is a key determinant of ligand binding.

J Biol Chem · 2014 · PMC4007430 · PMID 24644289

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highly significantno p-value reported
Notably, use of higher concentrations of sodium chlorate (150 m m ) resulted in more substantial and highly significant inhibition of ligand uptake and internalization by ACKR2-expressing HEK cells.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.