NOX2-generated oxidative stress is associated with severity of ultrasound liver steatosis in patients with non-alcoholic fatty liver disease.

BMC Gastroenterol · 2014 · PMC4014405 · PMID 24758604

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an increasing trendno p-value reported

Also in this clinical setting, an increasing trend of the mean levels of both urinary 8-iso-PGF2α and serum sNOX2-dp with increasing NAFLD severity was observed.

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a decreasing trendno p-value reported

A progressive, statistically significant increase (p < .001) of mean values of urinary 8-iso-PGF2α and of serum sNOX2-dp, CK-18, ALT, gamma-glutamil-transpeptidase (GGT) and HOMA-IR was observed from the group without fatty liver to the groups with mild, moderate and severe steatosis, while a decreasing trend was observed for serum adiponectin.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.