PRDE-1 is a nuclear factor essential for the biogenesis of Ruby motif-dependent piRNAs in C. elegans.

Genes Dev · 2014 · PMC4015492 · PMID 24696457

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highly significantP < 0.01actually significant

Moreover, gene set enrichment analysis using the entire array data confirmed statistically highly significant up-regulation of innate immunity genes in prg-1 relative to both wild type and prde-1 (permutation estimated P < 0.01) (Supplemental Fig.

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