conducted a mete-analysis on the associations between several COX-2 polymorphisms and breast cancer risk and suggested borderline significant increased risk of breast cancer was detected for rs5277 but no significant association was observed for the -765 G > C and 8473 C > T polymorphisms [ 15 ].
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Functional promoter -765 G > C variant in COX-2 gene is associated with the susceptibility of breast cancer in Chinese Han women.
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