Barely Significant
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Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type.

BMC Genomics · 2014 · PMC4028873 · PMID 24555763

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The sentences

highly significantp < 1×10 -308actually significant
All of the overlap between pairs of cohorts mentioned above was highly significant (Fisher’s exact p < 1×10 -308 ); however, a caveat of this analysis is that the four brain regions were sampled from the same set of individuals.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.