Decreased hippocampal volume and increased anxiety in a transgenic mouse model expressing the human CYP2C19 gene.

Mol Psychiatry · 2014 · PMC4031638 · PMID 23877834

Europe PMC DOI

hedged sentence

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

trending toward significanceP =0.056so close (0.05 < p ≤ 0.1)

In the open-field test, evaluation of the total distance travelled over 30 min in the novel environment showed significantly increased locomotor activity in 15-week-old CYP2C19Tg-Hem mice compared with Wt mice ( P =0.027), which was already trending toward significance at 7 weeks of age ( P =0.056; Figures 5a and b ).

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