borderline significanceP = 0.08
Figure 6A,B , and Table S6 show that when compared with OCL, ORP has significantly higher TCA cycle metabolites: α-ketoglutarate, fumarate, malate, and citrate, with ratios of 1.32–1.41 ( P = 0.001–0.02); and higher succinate and oxaloacetate with borderline significance ( P = 0.08–0.09).