Dissecting vancomycin-intermediate resistance in staphylococcus aureus using genome-wide association.

Genome Biol Evol · 2014 · PMC4040999 · PMID 24787619

Europe PMC DOI

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closest p · 0.0× alpha

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highly significantP = 8.78E-08actually significant

Genome-wide association studies (GWAS) of 55,977 single-nucleotide polymorphisms identified in one or more strains found one highly significant association ( P = 8.78E-08) between a nonsynonymous mutation at codon 481 (H481) of the rpoB gene and increased vancomycin MIC.

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