Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress.

A highly significant proportion of these genes (Figure 4A and B and Supplementary file 5) (599, hypergeometric P < 1e−16) are also within 25 kb of 961 TP53 binding sites, potentially representing direct TP53-induced target genes (Figure 4B and C ), many of which, such as CDKN1A , are associated with multiple TP53 sites.

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