In neuritic processes, an increase or at least an increasing trend with age in the percentages and volume densities of altered mitochondria was observed in the frontocentral cortex of APP23, APP48 and wild type mice (Additional file 2 k, Additional file 4 a, b).
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The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice.
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