highly significantp≤0.001
Nevertheless, chi-square tests identify highly significant differences in the distribution of all main functional roles across timepoints (p≤0.001), except for “central intermediary metabolism” (p = 0.02) and “unclassified proteins” (p = 0.4). “Protein synthesis”, “transport and binding proteins” and “energy metabolism” predominate across all samples, with “protein synthesis” being the most abundant role in most cases and one or the other of the latter two roles being the most abundant in a small fraction of the infants' samples.