Quantitative chemical proteomics identifies novel targets of the anti-cancer multi-kinase inhibitor E-3810.

Mol Cell Proteomics · 2014 · PMC4047469 · PMID 24696502

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a decreasing trendno p-value reported

Within this set, 22 proteins displayed a decreasing trend of SILAC ratio from sample A to sample D and a ratio value in sample D below the statistically significant threshold of two sigma levels (5%), so they were considered genuine E-3810 binders ( Table I and supplemental Fig.

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