marginally significantP = 0.052
Both of the subgroups with 3 ~ 4 risk alleles and 5 ~ 6 risk alleles showed marginally significant or significant associations with increased KD risk (OR = 1.32, 95% CI = 1.00–1.74, P = 0.052; OR = 2.93, 95% CI = 1.66–5.17, P < 0.001), and the Cochran-Armitage trend test indicated a significant dose effect with the ORs being increased with increasing numbers of risk alleles ( P trend < 0.001, Table 3 ).