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Effect of secular trends on age-related trajectories of cardiovascular risk factors: the Whitehall II longitudinal study 1985-2009.

Int J Epidemiol · 2014 · PMC4052135 · PMID 24464190

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a decreasing trendno p-value reported
Although the observed decline may be at least partially due to the wider use of statins in the past decades, particularly in the elderly, this could not explain a decreasing trend in the lower extremes of the distribution.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.