The use of longitudinal 18F-FET MicroPET imaging to evaluate response to irinotecan in orthotopic human glioblastoma multiforme xenografts.

PLoS One · 2014 · PMC4053391 · PMID 24918622

Europe PMC DOI

hedged sentences

0.0450

closest p · 0.9× alpha

0.0900

boldest claim

The sentences

borderline significantp = 0.045actually significant

However, the difference of the relative LAT1 expression was borderline significant with 1.6 fold higher LAT1 expression in GBM patients compared to the xenografts (744; 95% CI: 503–1099 vs. 467; 95% CI: 358–610; p = 0.045).

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a trend towards significancep = 0.09so close (0.05 < p ≤ 0.1)

206±16%, n = 4; p = 0.0049) in the CPT-11 group, although after one week there was only a trend towards significance between the treatment and the control group (127±7%, n = 7 and 147±8%, n = 7; p = 0.09).

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