highly significantP values < 1 × e -10
Although the differences between 10 (jMOSAiCS specific) and unenriched regions did not appear as pronounced as the differences between 11 (enriched according to both methods) versus 00 (unenriched according to both methods), the observed differences were highly significant ( P values < 1 × e -10 with both the t-test and Wilcoxon rank-sum test), indicating that these regions are enriched for H4K3me3.