Impact of lifetime opioid exposure on arterial stiffness and vascular age: cross-sectional and longitudinal studies in men and women.

BMJ Open · 2014 · PMC4054659 · PMID 24889849

Europe PMC DOI

hedged sentences

0.0546

closest p · 1.1× alpha

0.0546

boldest claim

The sentences

of borderline significancep=0.0546so close (0.05 < p ≤ 0.1)

While the CA : level 3 opioid exposure interaction is of borderline significance in all patients and women (p=0.0546 and 0.0568, but not in men) in the longitudinal study, the age : level 2 exposure is significant in all patients and men (p=0.0003 and 0.0110) and level 3 opioid exposure approaches significance in women as a factor and in interaction with age (p=0.0501 and 0.0547).

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highly significantno p-value reported

Online supplementary table S9 presents the results of a longitudinal regression of age-corrected indices of cardiovascular stiffness against time and opioid exposure quartile by gender, and notes a highly significant effect by exposure quartile in both genders.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.