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Waste water effluent contributes to the dissemination of CTX-M-15 in the natural environment.

J Antimicrob Chemother · 2014 · PMC4054988 · PMID 24797064

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a worrying trendno p-value reported
This is the first report of bla CTX-M-15 in UK river waters and represents a worrying trend as this gene is the most common ESBL in E. coli and Klebsiella spp . causing clinical disease. 4 Novel hosts were isolated across the Gammaproteobacteria, including Citrobacter braakii , A. media and P. fluorescens , none of which has previously been reported as a carrier of bla CTX-M-15 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.