This is the first report of bla CTX-M-15 in UK river waters and represents a worrying trend as this gene is the most common ESBL in E. coli and Klebsiella spp . causing clinical disease. 4 Novel hosts were isolated across the Gammaproteobacteria, including Citrobacter braakii , A. media and P. fluorescens , none of which has previously been reported as a carrier of bla CTX-M-15 .
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Waste water effluent contributes to the dissemination of CTX-M-15 in the natural environment.
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