Together with our findings of a borderline significant p-value for association between hTERT and Ki67 within progressor non-dysplasia, and no significance detected within the increasing levels of distorted morphology ( Table III ), it seems the association between proliferation and hTERT protein expression is lost during the development of dysplasia.
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Reduced hTERT protein levels are associated with DNA aneuploidy in the colonic mucosa of patients suffering from longstanding ulcerative colitis.
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