highly significantp = 0.007
Univariate survival analysis showed as highly significant prognostic factors for longer survival the following pretreatment characteristics (Table 3 ): Performans status 0–1 (HR = 2.1; p = 0.007), weight loss less than 10% (HR 2.58; p = 0.002), positive TTF-1 status (HR = 0.54; p = 0.03), early stage T0-T1 versus T2-3-4 (HR = 2.37; p = 0.0013), and absence of visceral involvement (HR = 1.8; p = 0.025).