Nosocomial transmission of C. difficile in English hospitals from patients with symptomatic infection.

Taking a total of a 20-week interval (as transmission events between hospital cases with an onset further than 20 weeks apart is assumed to be unlikely), the model revealed a highly significant Box-Pierce Q-statistic (X 2 = 54.59, degrees of freedom (df) = 20, p = 0.00005), indicating non-independence.

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