Serum C-X-C motif chemokine 13 is elevated in early and established rheumatoid arthritis and correlates with rheumatoid factor levels.

We found a highly significant relationship to IgM RF ( r = 0.45, P < 0.0001) (Figure 1 B), with a much weaker relationship to IgG ACPA ( r = 0.17, P = 0.03) (Figure 1 D).

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Log-transformed hsCRP (log CRP) and log CXCL13 showed only a trend toward significance ( P = 0.07) (Figure 2 A).

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