Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases.

Genome Med · 2014 · PMC4062055 · PMID 24598577

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highly significantno p-value reported

The only highly significant human-specific gain of binding affinity within this island was for Rfx1 (Regulatory factor X1, aka Enhancer factor C, V$ECF_Q6), with a significant human motif binding P -value of 0.042, and non-significant chimpanzee ( P = 0.635) and rhesus macaque ( P = 0.491) prediction (Additional file 7 ).

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