However, children that seem to have made a full recovery may also benefit from long-term monitoring for development of hypertension and proteinuria, as the extent of lost nephrons during the acute phase of the disease may be significant but masked by compensation of remaining nephrons. 80 aHUS, particularly the familial form, has been reported to be associated with a poor prognosis; without specific treatment, patients experience relapses and ongoing disease activity leading to end-stage kidney failure in most cases. 77 The diseas
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