Preventive effects of the angiotensin-converting enzyme inhibitor, captopril, on the development of azoxymethane-induced colonic preneoplastic lesions in diabetic and hypertensive rats.

Oncol Lett · 2014 · PMC4063600 · PMID 24959250

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may be significantno p-value reported

These aforementioned studies indicate that dysregulation of the renin-angiotensin system may be significant in Mets-related colorectal carcinogenesis and, therefore, an effective target for the chemoprevention of CRC, specifically in patients with Mets.

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