Methylated DNA and high total DNA levels in the serum of patients with breast cancer following neoadjuvant chemotherapy are predictive of a poor prognosis.

Oncol Lett · 2014 · PMC4063626 · PMID 24959284

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highly significantno p-value reported

However, the available data appears to indicate that met-DNA following NAC is a highly significant prognostic indicator for poor prognosis, as none of the patients that were positive for met-DNA attained pCR, and as many as 86% developed recurrence.

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