From the Table 3 results of ANOVA, response Y showed that the predicted values for all factors: buffer pH (X1), acetonitrile composition in mobile phase A (X2), acetonitrile composition in mobile phase B (X3), and flow rate (X4) were under the satisfactory value with the predicted model F-value of 8.67, which represented that the model is highly significant with the model p-value of 0.0151, indicating there is only a 1.51% chance that the model F-value is large due to noise.
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Development and Validation of a UPLC Method by the QbD-Approach for the Estimation of Rabeprazole and Levosulpiride from Capsules.
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