Lipid-induced insulin resistance led to lower pAS160 Ser341 and a nonsignificant trend for lower pAS160 Ser588 with unaltered IRS-1–PI3K, pAkt, or pS160 Thr642 .
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Postexercise improvement in insulin-stimulated glucose uptake occurs concomitant with greater AS160 phosphorylation in muscle from normal and insulin-resistant rats.
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